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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SQSTM1
All Species:
10.3
Human Site:
S277
Identified Species:
25.19
UniProt:
Q13501
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13501
NP_001135771.1
440
47687
S277
P
V
S
P
E
S
S
S
T
E
E
K
S
S
S
Chimpanzee
Pan troglodytes
XP_518154
440
47713
S277
P
V
S
P
E
S
S
S
T
E
E
K
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001102347
439
47572
S276
T
P
A
S
P
E
S
S
S
T
E
K
N
S
S
Dog
Lupus familis
XP_538580
688
72696
T357
V
S
P
G
G
S
S
T
E
D
R
G
S
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q64337
442
48144
G279
T
P
E
S
S
S
T
G
T
E
D
K
S
N
T
Rat
Rattus norvegicus
O08623
439
47663
G276
S
A
E
S
S
S
T
G
T
E
D
K
S
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506086
492
54053
S329
Q
G
G
S
Q
P
S
S
C
S
S
D
Q
N
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14199
599
65285
Q401
S
A
A
P
S
A
N
Q
S
N
V
P
S
A
N
Honey Bee
Apis mellifera
XP_392222
399
45715
K236
N
V
E
S
N
S
S
K
V
E
K
K
E
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795534
414
45119
R247
G
R
G
K
H
G
R
R
H
G
G
K
G
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.7
49.7
N.A.
90.7
91.3
N.A.
59.9
N.A.
N.A.
N.A.
N.A.
21.3
22.9
N.A.
30.6
Protein Similarity:
100
99.7
98.8
54.5
N.A.
94.3
94.5
N.A.
70.5
N.A.
N.A.
N.A.
N.A.
35.2
43.4
N.A.
42.5
P-Site Identity:
100
100
40
26.6
N.A.
33.3
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
40
N.A.
6.6
P-Site Similarity:
100
100
60
40
N.A.
60
53.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
53.3
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
20
0
0
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
20
10
0
0
0
% D
% Glu:
0
0
30
0
20
10
0
0
10
50
30
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
20
10
10
10
0
20
0
10
10
10
10
10
0
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
10
70
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
10
0
0
10
0
0
10
20
10
% N
% Pro:
20
20
10
30
10
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
10
0
0
0
0
10
0
10
% Q
% Arg:
0
10
0
0
0
0
10
10
0
0
10
0
0
0
20
% R
% Ser:
20
10
20
50
30
60
60
40
20
10
10
0
60
40
40
% S
% Thr:
20
0
0
0
0
0
20
10
40
10
0
0
0
0
20
% T
% Val:
10
30
0
0
0
0
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _